BDBM50437162 CHEMBL2401833

SMILES C[C@@H](Oc1c(N)ncc2c(coc12)C1=CCN(CC1)S(N)(=O)=O)c1c(Cl)ccc(F)c1Cl

InChI Key InChIKey=SOFIJJPAHAAJKO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437162   

TargetHepatocyte growth factor receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437162(CHEMBL2401833)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of cMET (unknown origin) using biotinylated poly(Glu,Tyr) as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437162(CHEMBL2401833)
Affinity DataIC50: 550nMAssay Description:Inhibition of cMET in human MKN45 cells assessed as phosphorylated MET levels after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed