BDBM50437159 CHEMBL2401817

SMILES Nc1ncc2c(coc2c1OC(CC=C)c1c(Cl)ccc(F)c1Cl)-c1cnn(c1)C1CCNCC1

InChI Key InChIKey=SLOCHCSZEMKCFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437159   

TargetHepatocyte growth factor receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437159(CHEMBL2401817)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of cMET in human MKN45 cells assessed as phosphorylated MET levels after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437159(CHEMBL2401817)
Affinity DataIC50: 110nMAssay Description:Inhibition of cMET (unknown origin) using biotinylated poly(Glu,Tyr) as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed