BDBM50437125 CHEMBL2403647

SMILES Cc1nc(cs1)C(=O)N1CCc2nc(sc2C1)C#Cc1ccccc1

InChI Key InChIKey=RLVCOLMHEOZGAK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437125   

TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50437125(CHEMBL2403647)
Affinity DataEC50:  220nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50437125(CHEMBL2403647)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-glutamate-induced activity after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed