BDBM50437011 CHEMBL2403025

SMILES CCNC(=O)C(C1CCN(CC1)c1ccc(NC(=O)Nc2ccccc2-c2ccccc2)cc1F)c1ccccc1

InChI Key InChIKey=IQGFSLKBISBLNR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437011   

TargetMicrosomal triglyceride transfer protein large subunit(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437011(CHEMBL2403025)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of MTP (unknown origin)-mediated triglyceride transfer from donor to acceptor vesicles preincubated for 5 mins followed by enzyme addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437011(CHEMBL2403025)
Affinity DataIC50: 27nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed