BDBM50437007 CHEMBL2403029

SMILES CCNC(=O)C(C1CCN(CC1)c1ccc(cc1F)C(=O)Nc1ccccc1-c1ccccc1)c1ccccc1

InChI Key InChIKey=HUUVMCDDBKCLOJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437007   

TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437007(CHEMBL2403029)
Affinity DataIC50: 45nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437007(CHEMBL2403029)
Affinity DataIC50: 33nMAssay Description:Inhibition of MTP (unknown origin)-mediated triglyceride transfer from donor to acceptor vesicles preincubated for 5 mins followed by enzyme addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed