BDBM50436967 CHEMBL2402272

SMILES CCOC(=O)c1cnc(N2CCN(CC2)C(=O)NS(=O)(=O)c2ccccc2C)c(Cl)c1

InChI Key InChIKey=INWVOWWBLBBQBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50436967   

TargetP2Y purinoceptor 12(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50436967(CHEMBL2402272)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) assessed as inhibition of GTPgammaS binding after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50436967(CHEMBL2402272)
Affinity DataIC50: 150nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed