BDBM50436849 CHEMBL2403768::US8999980, I-9

SMILES C[C@]1(CCOC(N)=N1)c1cc(NC(=O)c2ncc(Cl)cc2Cl)ccc1F

InChI Key InChIKey=CDNCNEWZGVRQRT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50436849   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM50436849(CHEMBL2403768 | US8999980, I-9)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50436849(CHEMBL2403768 | US8999980, I-9)
Affinity DataIC50: 900nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed