BDBM50436622 CHEMBL568708

SMILES CCOc1ccc2nc(S)sc2c1

InChI Key InChIKey=HOASVNMVYBSLSU-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50436622   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Rat)
Bar-Ilan University

Curated by ChEMBL

LigandBDBM50436622(CHEMBL568708)Copy SMILESCopy InChI

Affinity DataEC50:  7.61E+4nMAssay Description:Activation of AMPK in rat L6 cells assessed as increase of [3H]dGlc uptake after 5 hrsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
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TargetProteasome subunit beta type-8(Human)
Hungarian Academy of Sciences

Curated by ChEMBL

LigandBDBM50436622(CHEMBL568708)Copy SMILESCopy InChI

Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human chymotrypsin-like beta 5i subunit of iCP using suc-LLVY-AMC as flurogenic substrate for 90 mins by fluorescence-based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/20/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL