BDBM50436400 CHEMBL2397008

SMILES CC[C@@H](NC(=O)N1CC(=O)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1cc(co1)C(O)=O

InChI Key InChIKey=AJGOHHUCZZWOSX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50436400   

TargetNeutrophil elastase(Human)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50436400(CHEMBL2397008)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-Ala-Ala-Pro-Val-pNA as substrate preincubated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCathepsin G(Human)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50436400(CHEMBL2397008)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human neutrophil cathepsin G using Boc-Gln-Ala-Arg-MCA as substrate preincubated for 10 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50436400(CHEMBL2397008)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed