BDBM50436328 CHEMBL2398804

SMILES Cc1ccccc1[C@@H]1OC[C@]2(C)[C@H](CC[C@@]3(C)[C@H]2C[C@H](OC(=O)c2ccc(cc2)C#N)[C@@]2(C)Oc4cc(oc(=O)c4[C@H](O)[C@H]32)-c2cccnc2)O1

InChI Key InChIKey=LSDMSWMTGQIHRK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50436328   

TargetSterol O-acyltransferase 2(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50436328(CHEMBL2398804)
Affinity DataIC50: 12nMAssay Description:Inhibition of ACAT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50436328(CHEMBL2398804)
Affinity DataIC50: 7.28E+4nMAssay Description:Inhibition of ACAT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50436328(CHEMBL2398804)
Affinity DataIC50: 7.28E+4nMAssay Description:Inhibition of SOAT1 (unknown origin) expressed in CHO cells using [14C]oleic acid incubated for 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSterol O-acyltransferase 2(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50436328(CHEMBL2398804)
Affinity DataIC50: 12nMAssay Description:Inhibition of SOAT2 (unknown origin) expressed in CHO cells using [14C]oleic acid incubated for 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed