BDBM50436236 CHEMBL2398678

SMILES Clc1ccc(NC(=O)C2CCCN(C2)C(=O)c2cccc(c2)-c2ccco2)cc1

InChI Key InChIKey=HERLZBNILRVHQN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50436236   

TargetTransforming protein RhoA(Human)
College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50436236(CHEMBL2398678)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of RhoC-mediated pathway in human PC3 cells assessed as inhibition of SRE-regulated gene transcription by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTransforming protein RhoA(Human)
College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50436236(CHEMBL2398678)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of RhoC-mediated pathway in human SK-Mel-147 cells assessed as inhibition of SRE-regulated gene transcription by luciferase reporter gene ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed