BDBM50436122 CHEMBL2397471

SMILES [H][C@]12CCCN1C(=O)[C@@H](C)NC(=O)[C@@H](CCCCN)NC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CC3=CNC4=C3C=CC=C4)NC(=O)[C@@H](CC3=CC=C(O)C=C3)NC(=O)[C@@]([H])(CSSC[C@@H](N)C(=O)N[C@H](CC(N)=O)C(=O)N1)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@]([H])(NC(=O)[C@@H](CCC(O)=O)NC2=O)[C@H](C)O)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](CC1=CN=CN1)C(O)=O

InChI Key InChIKey=PETYOLVFAQBBFE-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50436122   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Southwest University

Curated by ChEMBL
LigandPNGBDBM50436122(CHEMBL2397471)
Affinity DataKd:  2.65E+4nMAssay Description:Binding affinity to MDM2 (25 to 109 amino acids) (unknown origin) after 30 mins by surface plasmon resosnance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Southwest University

Curated by ChEMBL
LigandPNGBDBM50436122(CHEMBL2397471)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of TMRA-p53 binding to MDM2 (25 to 109 amino acids) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed