BDBM50435998 CHEMBL2392183

SMILES COc1ccc(cn1)C(=O)Nc1cc(Br)cc2c1oc(cc2=O)C(O)=O

InChI Key InChIKey=FFRLOXKAKNBOMY-UHFFFAOYSA-N

Data  1 KI  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50435998   

TargetG-protein coupled receptor 55(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50435998(CHEMBL2392183)
Affinity DataIC50: 6.20E+3nMAssay Description:Antagonist activity at human GPR55 expressed in CHO cells assessed as inhibition of lysophosphotidylinositol-induced beta-arrestin recruitment preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50435998(CHEMBL2392183)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetG protein-coupled receptor GPR35(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50435998(CHEMBL2392183)
Affinity DataEC50:  991nMAssay Description:Agonist activity at rat GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50435998(CHEMBL2392183)
Affinity DataEC50:  4.98E+3nMAssay Description:Agonist activity at mouse GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50435998(CHEMBL2392183)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50435998(CHEMBL2392183)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed