BDBM50435778 CHEMBL2393162

SMILES O=C(NCc1cccnc1)Nc1ccc(cc1)S(=O)(=O)N1CCC2(CCCN2)CC1

InChI Key InChIKey=XPAAFTKNBOEGMR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435778   

TargetCytochrome P450 2C9(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50435778(CHEMBL2393162)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50435778(CHEMBL2393162)
Affinity DataIC50: 27nMAssay Description:Inhibition of NAMPT (unknown origin) assessed as NAM conversion to NMN preincubated for 15 mins prior to substrate addition measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed