BDBM50435736 CHEMBL2392552::US9266890, I-3

SMILES COc1cc(ccc1Nc1ncc2N(C)C(=O)CCN(C3CCCC3)c2n1)C(=O)NC1CCN(C)CC1

InChI Key InChIKey=JFRNFMQDZRWAQB-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435736   

TargetSerine/threonine-protein kinase PLK1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50435736(US9266890, I-3 | CHEMBL2392552)
Affinity DataKd:  0.570nMAssay Description:In vitro Plk1 binding assay: Ambit Kd values in nanomolar. Kd values generated by Ambit binding assay over a concentration range of the compound.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50435736(US9266890, I-3 | CHEMBL2392552)
Affinity DataIC50: 12nMAssay Description:Inhibition of PLK1 (unknown origin) using biotin-AGAGTVPESIHSFIGDGLV as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed