BDBM50435729 CHEMBL2392543

SMILES COc1cc(ccc1Nc1ncc2N(C)C(=O)[C@@](F)(CN(C3CCCC3)c2n1)C=C)C(=O)NC1CCN(C)CC1

InChI Key InChIKey=RBXLZSWSJTUVKC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50435729   

TargetSerine/threonine-protein kinase PLK1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50435729(CHEMBL2392543)
Affinity DataIC50: 170nMAssay Description:Inhibition of PLK1 (unknown origin) using biotin-AGAGTVPESIHSFIGDGLV as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed