BDBM50435676 CHEMBL2391938

SMILES COc1ccc(C(=O)NC2CC2)c(OC[C@@H](O)CN2CCC3(Cc4cc(Cl)ccc4O3)CC2)c1

InChI Key InChIKey=MVACDKPCOURBQW-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435676   

TargetMacrophage inflammatory protein-1 alpha receptor(Rat)
Astrazeneca

Curated by ChEMBL

LigandBDBM50435676(CHEMBL2391938)Copy SMILESCopy InChI

Affinity DataIC50: 79nMAssay Description:Antagonist activity at rat CCR1More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
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TargetC-C chemokine receptor type 1(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50435676(CHEMBL2391938)Copy SMILESCopy InChI

Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL