BDBM50435606 CHEMBL2390996

SMILES ONC(=O)C=Cc1ccc2OC3(CCN(CCc4ccccc4)CC3)CC(=O)c2c1

InChI Key InChIKey=APXBMYOOUQRNRA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50435606   

TargetHistone deacetylase 6(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50435606(CHEMBL2390996)
Affinity DataIC50: 138nMAssay Description:Inhibition of recombinant human HDAC6 after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50435606(CHEMBL2390996)
Affinity DataIC50: 199nMAssay Description:Inhibition of recombinant human HDAC2 after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50435606(CHEMBL2390996)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human HDAC3 after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50435606(CHEMBL2390996)
Affinity DataIC50: 113nMAssay Description:Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50435606(CHEMBL2390996)
Affinity DataIC50: 130nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed