BDBM50435110 CHEMBL2391535

SMILES CC(=O)N1CCc2c(C1)c1ccccc1n2CC(O)=O

InChI Key InChIKey=YUHNDOWVUGYFBI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50435110   

TargetProstaglandin D2 receptor 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435110(CHEMBL2391535)
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50435110(CHEMBL2391535)
Affinity DataIC50: 20nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50435110(CHEMBL2391535)
Affinity DataIC50: 21nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50435110(CHEMBL2391535)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed