BDBM50434750 CHEMBL2385596

SMILES CN1CCN(CC1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12

InChI Key InChIKey=XBGWAKUQSRNWMA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50434750   

TargetTGF-beta receptor type-1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434750(CHEMBL2385596)
Affinity DataIC50: 75nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBone morphogenetic protein 4(Mouse)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434750(CHEMBL2385596)
Affinity DataIC50: 25nMAssay Description:Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434750(CHEMBL2385596)
Affinity DataIC50: 15nMAssay Description:Inhibition of TGFBR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434750(CHEMBL2385596)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target5'-AMP-activated protein kinase subunit beta-1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434750(CHEMBL2385596)
Affinity DataIC50: 960nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetActivin receptor type-1B(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434750(CHEMBL2385596)
Affinity DataIC50: 183nMAssay Description:Inhibition of ALK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed