BDBM50433903 CHEMBL2380586

SMILES Cn1cc(cn1)-c1cc2[nH]nc(-c3cccc(c3)S(N)(=O)=O)c2cc1NC1CCCCC1

InChI Key InChIKey=PUJKNBHSGMNWBW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50433903   

TargetDual specificity protein kinase TTK(Human)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50433903(CHEMBL2380586)
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-fused full length human TTK compound pre-incubated for 15 mins prior ATP addition by MBP-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50433903(CHEMBL2380586)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human PLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50433903(CHEMBL2380586)
Affinity DataIC50: 21nMAssay Description:Inhibition of FLAG-tagged MPS1 phosphorylation in human RERF-LC-AI Tet-off cells after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50433903(CHEMBL2380586)
Affinity DataIC50: 10nMAssay Description:Inhibition of MPS1 (unknown origin) using biotin-labeled AGAGLARHTDDEMTGYVA as substrate after 90 mins by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed