BDBM50433769 CHEMBL2381600

SMILES CN[C@H]1CC[C@@H](CC1)Nc1ncc(C(N)=O)n2cc(nc12)-c1ccc(Cl)cc1

InChI Key InChIKey=NVNJXYOVWGMPAO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50433769   

TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433769(CHEMBL2381600)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433769(CHEMBL2381600)
Affinity DataIC50: 890nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed