BDBM50433633 CHEMBL2380832

SMILES Fc1ccc(cc1F)C(=O)Nc1ccc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)cc1

InChI Key InChIKey=ZBPGILZGNLFHOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50433633   

TargetAurora kinase A(Human)
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50433633(CHEMBL2380832)
Affinity DataIC50: 7nMAssay Description:Inhibition of aurora-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50433633(CHEMBL2380832)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed