BDBM50433565 CHEMBL2381567

SMILES CN1CCC[C@H]1COC(=O)c1ccc(OCc2ccccc2)nc1

InChI Key InChIKey=PKQIBCQLDRUHEO-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50433565   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Chile

Curated by ChEMBL
LigandPNGBDBM50433565(CHEMBL2381567)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Chile

Curated by ChEMBL
LigandPNGBDBM50433565(CHEMBL2381567)
Affinity DataIC50: 166nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Chile

Curated by ChEMBL
LigandPNGBDBM50433565(CHEMBL2381567)
Affinity DataKi:  2.95E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Chile

Curated by ChEMBL
LigandPNGBDBM50433565(CHEMBL2381567)
Affinity DataIC50: 5.91E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed