BDBM50433410 CHEMBL2380647

SMILES O[C@@]12CC3CC(C1)[C@H](NC(=O)N1CCN(c4ccc(cn4)N4CCN(CC4)S(=O)(=O)C4CC4)c4ccccc14)C(C3)C2

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50433410   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433410(CHEMBL2380647)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433410(CHEMBL2380647)
Affinity DataIC50: 21nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433410(CHEMBL2380647)
Affinity DataIC50: 21nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed