BDBM50433409 CHEMBL2380646

SMILES CC(=O)N1CCN(CC1)c1ccc(nc1)N1CCN(C(=O)N[C@H]2C3CC4CC2C[C@](O)(C4)C3)c2ccccc12

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50433409   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433409(CHEMBL2380646)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433409(CHEMBL2380646)
Affinity DataIC50: 11nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433409(CHEMBL2380646)
Affinity DataIC50: 65nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed