BDBM50432829 CHEMBL2171700

SMILES COc1nn(-c2ccc(Oc3ccccc3)cc2)c(=O)o1

InChI Key InChIKey=YAKCIFSNRAIAJM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50432829   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50432829(CHEMBL2171700)
Affinity DataIC50: 720nMAssay Description:Inhibition of FAAH in Sprague-Dawley rat brain microsomes assessed as N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide conversion to 4-pyren-1-ylbutanoic ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50432829(CHEMBL2171700)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant MAGL-mediated 1,3-dihydroxypropan-1-yl 4-pyren-1-ylbutanoate conversion to 4-pyren-1-ylbutanoic acid preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50432829(CHEMBL2171700)
Affinity DataIC50: 65nMAssay Description:Inhibition of FAAH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50432829(CHEMBL2171700)
Affinity DataIC50: 78nMAssay Description:Inhibition of MAGL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50432829(CHEMBL2171700)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of His-tagged human MAGL expressed in Escherichia coli BL21(DE3) assessed as reduction in arachidonic acid production from 2-arachidonoylg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50432829(CHEMBL2171700)
Affinity DataIC50: 31nMAssay Description:Inhibition of His-tagged human MAGL expressed in Escherichia coli BL21(DE3) assessed as reduction in arachidonic acid production from 2-arachidonoylg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50432829(CHEMBL2171700)
Affinity DataIC50: 78nMAssay Description:Inhibition of MAGL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed