BDBM50432486 CHEMBL2349349

SMILES c1cc(cc(c1)NS(=O)(=O)c2cccs2)C3=CSC(=O)N3

InChI Key InChIKey=PSOFLBHWUXTHTE-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50432486   

TargetBromodomain-containing protein 4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50432486(CHEMBL2349349)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of BRD4(1) (unknown origin) incubated for 4 hrs by (+)-JQ1 fluorescent ligand based fluorescence anisotrophyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50432486(CHEMBL2349349)
Affinity DataIC50: 4.10E+3nMAssay Description:Displacement of FITC-labeled (+)-JQ1 from bromodomain BRD4(1) (unknown origin) expressed in Escherichia coli BL21(DE3) after 4 hrs by fluorescence an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed