BDBM50432301 CHEMBL2347852

SMILES FC(F)(F)c1cc(COC[C@@]2(CCCNCC2)c2ccccc2)cc(c1)C(F)(F)F

InChI Key InChIKey=QLXHEEVESGWCHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50432301   

TargetSubstance-P receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50432301(CHEMBL2347852)
Affinity DataIC50: 2.5nMAssay Description:Displacement of [125I]substance P from human recombinant NK1 receptor expressed in human U373 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50432301(CHEMBL2347852)
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I]RTI-55 from human recombinant SERT expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed