BDBM50431702 CHEMBL2349528

SMILES Clc1cccc(NC(=O)c2noc3CCCc23)c1

InChI Key InChIKey=YEYBSOOLSUEJAG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50431702   

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431702(CHEMBL2349528)
Affinity DataIC50: 63nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50431702(CHEMBL2349528)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of N-terminal hexa-His tagged human APE1 expressed in Escherichia coli BL21 (Rosetta) using fluorescein-dabcyl-containing oligonucleotide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed