BDBM50431475 CHEMBL2348327

SMILES Fc1ccccc1NC(C(=O)N1CCCC1c1ccccc1F)c1ccc(cc1)-c1cncnc1

InChI Key InChIKey=UBTNGNPZFOXKPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431475   

TargetTransient receptor potential M8 protein(Dog)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50431475(CHEMBL2348327)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium influx incubated for 5 mins prior to icil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed