BDBM50431474 CHEMBL2348326

SMILES OC(=O)c1ccc(cc1)-c1ccc(cc1)C(Nc1ccccc1F)C(=O)N1CCC[C@H]1c1ccccc1F

InChI Key InChIKey=XJXZQMRLKYIBCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431474   

TargetTransient receptor potential M8 protein(Dog)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50431474(CHEMBL2348326)
Affinity DataIC50: 56nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium influx incubated for 5 mins prior to icil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed