BDBM50431467 CHEMBL2348305

SMILES c1cc(ccc1O)Oc2c(cc(cc2I)C[C@@H](CO)N)I

InChI Key InChIKey=NKOSKXJRVWVXRI-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50431467   

TargetProliferating cell nuclear antigen(Human)
Jiangxi University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431467BDBM50431467(CHEMBL2348305)
Affinity DataKi:  70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetProliferating cell nuclear antigen(Human)
Jiangxi University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431467BDBM50431467(CHEMBL2348305)
Affinity DataIC50: 800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetProliferating cell nuclear antigen(Human)
Jiangxi University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431467BDBM50431467(CHEMBL2348305)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to full length human PCNA expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with N-terminal 5-carboxyflu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA ligase 1(Human)
University of Allahabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431467BDBM50431467(CHEMBL2348305)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DNA ligase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProliferating cell nuclear antigen(Human)
Jiangxi University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431467BDBM50431467(CHEMBL2348305)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProliferating cell nuclear antigen(Human)
Jiangxi University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431467BDBM50431467(CHEMBL2348305)
Affinity DataIC50: 2.00E+4nMAssay Description:Binding affinity to monoubiquitinated PCNA derived from human GM04312 cells assessed as inhibition of interaction with His8-tagged DNA polymerase eta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)