BDBM50431271 CHEMBL2333033::US9428465, 4

SMILES CCCCCCNC(=O)n1cc(c(=O)[nH]c1=O)C(F)(F)F

InChI Key InChIKey=LLRJQFMAXXADBL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50431271   

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431271(CHEMBL2333033 | US9428465, 4)
Affinity DataIC50: 10nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431271(CHEMBL2333033 | US9428465, 4)
Affinity DataIC50: 12nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431271(CHEMBL2333033 | US9428465, 4)
Affinity DataIC50: 12nMAssay Description:Inhibition of rat acid ceramidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431271(CHEMBL2333033 | US9428465, 4)
Affinity DataIC50: 7.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed