BDBM50431264 CHEMBL2333040::US9428465, 14

SMILES CCCCCCNC(=O)n1cc(-c2ccccc2)c(=O)[nH]c1=O

InChI Key InChIKey=BBZFIIUFDXKSHN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50431264   

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431264(CHEMBL2333040 | US9428465, 14)
Affinity DataIC50: 177nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetAcid ceramidase(Human)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431264(CHEMBL2333040 | US9428465, 14)
Affinity DataIC50: 155nMpH: 4.5Assay Description:A hAC protein preparation (10 μg) was preincubated with inhibitors (final DMSO concentration 1%) in assay buffer (100 mM sodium phosphate, 0.1% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431264(CHEMBL2333040 | US9428465, 14)
Affinity DataIC50: 177nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed