BDBM50431227 CHEMBL2333024

SMILES CC(C)[C@H](NC(=O)c1cccnc1)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=QWMROLCIGVLHNY-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50431227   

TargetProlyl endopeptidase(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431227(CHEMBL2333024)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human PREP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431227(CHEMBL2333024)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human FAP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431227(CHEMBL2333024)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DPP9 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431227(CHEMBL2333024)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DPP8 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431227(CHEMBL2333024)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DPP4 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431227(CHEMBL2333024)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of FAP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431227(CHEMBL2333024)
Affinity DataKi:  0.730nMAssay Description:Competitive inhibition of human PREP using Suc-GP-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed