BDBM50430986 CHEMBL2338312

SMILES CC[C@H](C)[C@H]1[C@@H](OC1=O)C(=O)N[C@H]1C[C@H]1C[C@@H](CCc1ccccc1)NC(=O)[C@H](C)NC(=O)OCc1ccccc1

InChI Key InChIKey=YUZQDEBWPUFQAF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50430986   

TargetProteasome subunit beta type-5(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50430986(CHEMBL2338312)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50430986(CHEMBL2338312)
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of caspase-like activity of human 20S proteasome beta 1 subunit using Ac-nLPnLD-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50430986(CHEMBL2338312)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit using Ac-RLR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed