BDBM50430570 CHEMBL2337363

SMILES Nc1nc(Nc2ccc(Cl)cc2)c2c(n1)[nH]c1cccc(Cl)c21

InChI Key InChIKey=VJQBMSSVRPHXIT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50430570   

TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50430570(CHEMBL2337363)
Affinity DataIC50: 1.96E+5nMAssay Description:Inhibition of PDGFRbeta in human SF539 cells assessed as inhibition of PDGFR-BB-induced tyrosine phosphorylation incubated for 60 mins prior to EGF-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50430570(CHEMBL2337363)
Affinity DataIC50: 6.36E+4nMAssay Description:Inhibition of EGFR in human A431 cells assessed as inhibition of EGF-induced tyrosine phosphorylation incubated for 60 mins prior to EGF-activation m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50430570(CHEMBL2337363)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of VEGFR2 in human U251 cells assessed as inhibition of VEGF-induced tyrosine phosphorylation incubated for 60 mins prior to VEGF-activati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed