BDBM504304 3α,7α,11β-rihydroxy-6α-ethyl-5β-cholan-24-O-sulphate, sodium salt ::US11034717, Compound 5

SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCCOS(=O)(=O)O[Na])[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12

InChI Key InChIKey=DQERVEMYTKUQHX-UHFFFAOYSA-M

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 504304   

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  15nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  15nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  15nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Mouse)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  120nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Rat)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  140nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetFMR1 autosomal homolog 1(Dog)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  730nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent