BDBM50430280 CHEMBL2332936

SMILES CC(=O)Nc1ccc(O)cc1OC[C@@H](O)CN1CCC2(Cc3cc(F)ccc3O2)CC1

InChI Key InChIKey=DHMMQCJCZXAHQH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50430280   

TargetC-C chemokine receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50430280(CHEMBL2332936)
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50430280(CHEMBL2332936)
Affinity DataIC50: 0.520nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cells after 1.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50430280(CHEMBL2332936)
Affinity DataIC50: 0.520nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed