BDBM50430276 CHEMBL2332942

SMILES CC(=O)Nc1ccc(O)cc1OC[C@@H](N)CN1CCC2(Cc3ccccc3O2)CC1

InChI Key InChIKey=VGIMKOQYMXCKHI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430276   

TargetC-C chemokine receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50430276(CHEMBL2332942)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50430276(CHEMBL2332942)
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cells after 1.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed