BDBM50429896 CHEMBL2332918

SMILES Cc1nc2ccc(cc2[nH]1)-c1ccc2OCCN(Cc2c1)C(=O)c1ccc(cc1)C(=O)C(F)(F)F

InChI Key InChIKey=IXENPKUVLGSVDO-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429896   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Exelixis

Curated by ChEMBL

LigandBDBM50429896(CHEMBL2332918)Copy SMILESCopy InChI

Affinity DataIC50: 89nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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