BDBM50429891 CHEMBL2333366

SMILES FC(F)(F)C(=O)c1ccc(cc1)C(=O)N1CCOc2ccc(cc2C1)-c1cnc2ccccc2c1

InChI Key InChIKey=BRPVOIKSYPEHFJ-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50429891   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Exelixis

Curated by ChEMBL

LigandBDBM50429891(CHEMBL2333366)Copy SMILESCopy InChI

Affinity DataIC50: 398nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetSerine/threonine-protein kinase mTOR(Human)
Sichuan University

Curated by ChEMBL

LigandBDBM50429891(CHEMBL2333366)Copy SMILESCopy InChI

Affinity DataIC50: 95nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/21/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Exelixis

Curated by ChEMBL

LigandBDBM50429891(CHEMBL2333366)Copy SMILESCopy InChI

Affinity DataIC50: 398nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/21/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL