BDBM50429705 CHEMBL2336321::US9102670, 3ad

SMILES CNC(=O)c1cc(ccc1OC)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1CCOC[C@@H]1C

InChI Key InChIKey=PPYBSQAQOAIKSQ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50429705   

TargetSerine/threonine-protein kinase mTOR(Human)
Kudos Pharmaceuticals

US Patent

LigandBDBM50429705(CHEMBL2336321 | US9102670, 3ad)Copy SMILESCopy InChI

Affinity DataIC50: 66nMT: 2°CAssay Description:The assay used AlphaScreen technology (Gray et al., Analytical Biochemistry, 2003, 313: 234-245) to determine the ability of test compounds to inhibi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/4/2016
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50429705(CHEMBL2336321 | US9102670, 3ad)Copy SMILESCopy InChI

Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL