BDBM50429702 CHEMBL2336326::US9102670, 8a

SMILES C[C@H]1COCCN1c1nc(N2CCOC[C@@H]2C)c2ccc(nc2n1)-c1cccc(c1)C(=O)NCCO

InChI Key InChIKey=OMMTWAGHTAHDIF-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50429702   

TargetSerine/threonine-protein kinase mTOR(Human)
Kudos Pharmaceuticals

US Patent

LigandBDBM50429702(CHEMBL2336326 | US9102670, 8a)Copy SMILESCopy InChI

Affinity DataIC50: 28nMT: 2°CAssay Description:The assay used AlphaScreen technology (Gray et al., Analytical Biochemistry, 2003, 313: 234-245) to determine the ability of test compounds to inhibi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
4/4/2016
Entry Details
Copy Entry DOIGo to US Patent

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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50429702(CHEMBL2336326 | US9102670, 8a)Copy SMILESCopy InChI

Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL