BDBM50429524 CHEMBL2333326

SMILES Clc1ccc(Cn2ccnc2)c2c1oc1ccccc1c2=O

InChI Key InChIKey=HJWKBORBWDDYTP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50429524   

TargetAromatase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50429524(CHEMBL2333326)
Affinity DataIC50: 480nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]androstenedione as substrate by 3H2O-methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50429524(CHEMBL2333326)
Affinity DataIC50: 260nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-expressing rat NADPH-P450-reductase using progesterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50429524(CHEMBL2333326)
Affinity DataIC50: 3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50429524(CHEMBL2333326)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed