BDBM50429046 CHEMBL2334882::US9359372, DC037081

SMILES COc1c(O)ccc2C[C@@H]3N(CCc4cc5CCOc5cc34)Cc12

InChI Key InChIKey=HYIGJQLIWSXNQW-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50429046   

TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50429046(CHEMBL2334882 | US9359372, DC037081)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor (unknown origin) expressed in human HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50429046(CHEMBL2334882 | US9359372, DC037081)
Affinity DataKi:  17.3nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50429046(CHEMBL2334882 | US9359372, DC037081)
Affinity DataKi:  147nM ΔG°:  -9.47kcal/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50429046(CHEMBL2334882 | US9359372, DC037081)
Affinity DataKi:  480nMAssay Description:Displacement of [3H]Ketanserin from 5-HT2A receptor (unknown origin) expressed in HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50429046(CHEMBL2334882 | US9359372, DC037081)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor (unknown origin) expressed in HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed