BDBM50429044 CHEMBL2334893::US9359372, DC037029

SMILES COc1cc2CCN3Cc4cc5OCOc5cc4C[C@H]3c2cc1O

InChI Key InChIKey=CIEGYDLRUMZWQS-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50429044   

TargetD(1A) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50429044(CHEMBL2334893 | US9359372, DC037029)
Affinity DataKi:  4.20nM ΔG°:  -11.6kcal/mole IC50: 8.19nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50429044(CHEMBL2334893 | US9359372, DC037029)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor (unknown origin) expressed in human HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50429044(CHEMBL2334893 | US9359372, DC037029)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor (unknown origin) expressed in human HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50429044(CHEMBL2334893 | US9359372, DC037029)
Affinity DataKi:  32.2nM ΔG°:  -10.4kcal/mole IC50: 91.1nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent