BDBM50428519 CHEMBL2336619

SMILES Cc1ccc(cc1)-c1cc(CO)nn1-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=SIRBZAXVIYKVEZ-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50428519   

TargetProstaglandin G/H synthase 2(Human)
Technische Universitat Dresden

Curated by ChEMBL
LigandPNGBDBM50428519(CHEMBL2336619)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of recombinant human COX-2 assessed as reduction of prostaglandin-G2 to prostaglandin-H2 and oxidation of 10-acetyl-3,7-dihydroxyphenoxazi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Technische Universitat Dresden

Curated by ChEMBL
LigandPNGBDBM50428519(CHEMBL2336619)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine COX-1 assessed as reduction of prostaglandin-G2 to prostaglandin-H2 and oxidation of 10-acetyl-3,7-dihydroxyphenoxazine to resoru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50428519(CHEMBL2336619)
Affinity DataKi:  22nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 10 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50428519(CHEMBL2336619)
Affinity DataKi:  176nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 10 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50428519(CHEMBL2336619)
Affinity DataKi:  1.51E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 10 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed