BDBM50428349 CHEMBL2331726

SMILES COC(=O)c1ccc(cc1NC(=O)c1ccc2ncccc2c1)-c1ccc(CN2CCc3ccccc3C2)cc1

InChI Key InChIKey=AKAMCNVSSDZPIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50428349   

TargetATP-dependent translocase ABCB1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50428349(CHEMBL2331726)
Affinity DataIC50: 4.49E+3nMAssay Description:Inhibition of ABCB1 in human KBV1 cells after 10 mins by Calcein-AM microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50428349(CHEMBL2331726)
Affinity DataIC50: 641nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed